t-cell acute lymphoblastic leukemia with del (7) (q11.2q22) and aberrant expression of myeloid markers.
نویسندگان
چکیده
t cell acute lymphoblastic leukemia (all) is an invasive disease with a higher incidence in children and adolescents. in terms of immunophenotype, t-all is positive for cd2, cd7, cd34 and hla-dr, and the level of these markers is increased with increasing age. in addition, the myeloid markers (cd13, cd33) are sometimes expressed in t-all. in this study, we introduce a rare case of a 28-year-old woman with t-all with aberrant expression of myeloid markers (cd13), without lymphadenopathy and with 94% blasts in bone marrow specimens. the patient has the rare karyotype of 46,xx del(7)(q11.2q22). the presence of del7 is a rare phenomenon in t-all.
منابع مشابه
T-cell Acute Lymphoblastic Leukemia with del (7) (q11.2q22) and Aberrant Expression of Myeloid Markers
T cell acute lymphoblastic leukemia (ALL) is an invasive disease with a higher incidence in children and adolescents. In terms of Immunophenotype, T-ALL is positive for CD2, CD7, CD34 and HLA-DR, and the level of these markers is increased with increasing age. In addition, the myeloid markers (CD13, CD33) are sometimes expressed in T-ALL. In this study, we introduce a rare case of a 28-year-old...
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عنوان ژورنال:
international journal of hematology-oncology and stem cell researchجلد ۷، شماره ۴، صفحات ۴۰-۴۴
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